Cart
sales@molnova.com
PACAP (1-38), human, ovine, rat TFA
CAS No. ——
PACAP (1-38), human, ovine, rat TFA ( Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA) )
Catalog No. M29753 CAS No. ——
PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NamePACAP (1-38), human, ovine, rat TFA
-
NoteResearch use only, not for human use.
-
Brief DescriptionPACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
-
DescriptionPACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
-
In Vitro——
-
In Vivo——
-
SynonymsPituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
-
PathwayOthers
-
TargetOther Targets
-
RecptorIC50: 4 nM (PACAP type I receptor), 2 nM (PACAP type II receptor VIP1), and 1 nM (PACAP type II receptor VIP2)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight4648.28
-
Molecular FormulaC203H331N63O53S.C2HF3O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameSequence:His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Gourlet P, et al. Fragments of pituitary adenylate cyclase activating polypeptide discriminate between type I and II recombinant receptors. Eur J Pharmacol. 1995 Dec 4;287(1):7-11.
molnova catalog
related products
-
Cephalosporin C zinc...
Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.?
-
Pseudoginsenoside RT...
Pseudoginsenoside RT1, isolated from the fruit of Randia siamensis, exhibits acute ichthyotoxic activity.
-
N-(p-Tosyl)-GPR-pNA ...
N-(p-Tosyl)-GPR-pNA acetate is a colorimetric substrate for thrombin that can act as a measure of thrombin activity.
